BODIPYI
Based on 1 Customer Validation
BODIPYI is the a BODIPY derivative. BODIPYI reveals a high O2 quantum yield and exhibits phototoxicity that inhibits HeLa with an IC50 of 0.6 μg/mL. BODIPYI nanoarticles can be taken up by HeLa, producing fluorescence signals in the cells, and can be used as cell imaging agent. BODIPYI nanoarticles exhibit antitumor efficacy in mouse models.
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- CAS 番号: 1083009-44-2
- 分子式: C19H17BF2I2N2
- 分子量:575.97
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEp-2 | IC50 |
>400 μM
Compound: 1a
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Dark toxicity in human Hep2 cells after 24 hrs by Cell Titre Blue assay
Dark toxicity in human Hep2 cells after 24 hrs by Cell Titre Blue assay
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[PMID: 23928070] |
| HEp-2 | IC50 |
27 μM
Compound: 1a
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Phototoxicity in human Hep2 cells incubated for 24 hrs followed by 1.5 J/cm'2 light irradiation for 20 mins measured after 24 hrs by Cell Titre Blue assay
Phototoxicity in human Hep2 cells incubated for 24 hrs followed by 1.5 J/cm'2 light irradiation for 20 mins measured after 24 hrs by Cell Titre Blue assay
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[PMID: 23928070] |
化学情報
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CAS 番号 1083009-44-2
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性状 Solid
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分子量 575.97
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分子式 C19H17BF2I2N2
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SMILES
CC(C(I)=C1C)=C(N1[B-]2(F)F)C(C3=CC=CC=C3)=C4[N+]2=C(C)C(I)=C4C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
プロトコル
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Patient-Derived Xenograft (PDX)
Patient-derived xenograft (PDX) models are generated by engrafting primary human tumor tissue directly into immunodeficient mice, allowing in vivo propagation of patient tumor biology without initial in vitro adaptation. These models are used to preserve key histopathological and molecular characteristics of the original tumor and enable assessment of tumor growth dynamics and therapeutic response in a living organism. The biological readout is tumor engraftment and subsequent growth in the murine host, which reflects the ability of human tumor cells to survive, vascularize, and expand in an immunocompromised microenvironment.
純度とドキュメンテーション
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データシート (286 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
BODIPYI 関連分類
HY-W112239 関連分類
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