Biotin-EDA
Based on 1 Customer Validation
Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.76%
- CAS 番号: 111790-37-5
- 分子式: C12H22N4O2S
- 分子量:286.39
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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Alkyl-Chain |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 111790-37-5
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性状 Solid
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分子量 286.39
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分子式 C12H22N4O2S
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Color White to off-white
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SMILES
O=C(NCCN)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 50 mg/mL (174.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4917 mL | 17.4587 mL | 34.9174 mL | 87.2935 mL |
| 5 mM | 0.6983 mL | 3.4917 mL | 6.9835 mL | 17.4587 mL | |
| 10 mM | 0.3492 mL | 1.7459 mL | 3.4917 mL | 8.7294 mL | |
| 15 mM | 0.2328 mL | 1.1639 mL | 2.3278 mL | 5.8196 mL | |
| 20 mM | 0.1746 mL | 0.8729 mL | 1.7459 mL | 4.3647 mL | |
| 25 mM | 0.1397 mL | 0.6983 mL | 1.3967 mL | 3.4917 mL | |
| 30 mM | 0.1164 mL | 0.5820 mL | 1.1639 mL | 2.9098 mL | |
| 40 mM | 0.0873 mL | 0.4365 mL | 0.8729 mL | 2.1823 mL | |
| 50 mM | 0.0698 mL | 0.3492 mL | 0.6983 mL | 1.7459 mL | |
| 60 mM | 0.0582 mL | 0.2910 mL | 0.5820 mL | 1.4549 mL | |
| 80 mM | 0.0436 mL | 0.2182 mL | 0.4365 mL | 1.0912 mL | |
| 100 mM | 0.0349 mL | 0.1746 mL | 0.3492 mL | 0.8729 mL |
Biotin-EDA 関連分類
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