BML264
Based on 1 Customer Validation
BML264 ((E)-N-(p-amylcinnamoyl) anthranilic acid) is an agonist for TREK-1. BML264 can be used to study diseases associated with TASK1 dysfunction.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.1%
- CAS 番号: 99196-74-4
- 分子式: C21H23NO3
- 分子量:337.41
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
28 μM
Compound: ACA
|
Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assay
Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assay
|
[PMID: 30878828] |
| HEK293 | IC50 |
1.7 μM
Compound: ACA
|
Inhibition of human TRPM2 expressed in HEK293 cells assessed as inhibition of H2O2-induced intracellular calcium level by patch clamp technique
Inhibition of human TRPM2 expressed in HEK293 cells assessed as inhibition of H2O2-induced intracellular calcium level by patch clamp technique
|
[PMID: 24304219] |
化学情報
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CAS 番号 99196-74-4
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性状 Solid
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分子量 337.41
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分子式 C21H23NO3
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Color White to off-white
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SMILES
O=C(O)C1=CC=CC=C1NC(/C=C/C2=CC=C(CCCCC)C=C2)=O
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別名
(E)-N-(p-Amylcinnamoyl) anthranilic acid
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
純度とドキュメンテーション
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データシート (263 KB)
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SDS (458 KB)
- English - EN (458 KB)
- Français - FR (458 KB)
- Deutsch - DE (458 KB)
- Norwegian - NO (458 KB)
- Español - ES (458 KB)
- Swedish - SV (458 KB)
- Italian - IT (458 KB)
- Korean - KR (458 KB)
- Portuguese - PT (458 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)