BMS-496
Based on 1 Customer Validation
BMS-496 is adualDGKα/ζlipid kinase inhibitor, with theIC50of 0.09 (DGKα) and 0.006 μM (DGKζ).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.72%
- CAS 番号: 2407854-31-1
- 分子式: C26H22BrF2N5O3
- 分子量:570.39
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
0.09, 0.006 μM (DGKα,DGKζ)[1].
化学情報
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CAS 番号 2407854-31-1
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性状 Solid
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分子量 570.39
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分子式 C26H22BrF2N5O3
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Color Light yellow to yellow
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SMILES
CN(C1=CC=C(Br)N=C1C(N2CCN(C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC2)=C5[N+]([O-])=O)C5=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (175.32 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
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- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7532 mL | 8.7659 mL | 17.5319 mL | 43.8297 mL |
| 5 mM | 0.3506 mL | 1.7532 mL | 3.5064 mL | 8.7659 mL | |
| 10 mM | 0.1753 mL | 0.8766 mL | 1.7532 mL | 4.3830 mL | |
| 15 mM | 0.1169 mL | 0.5844 mL | 1.1688 mL | 2.9220 mL | |
| 20 mM | 0.0877 mL | 0.4383 mL | 0.8766 mL | 2.1915 mL | |
| 25 mM | 0.0701 mL | 0.3506 mL | 0.7013 mL | 1.7532 mL | |
| 30 mM | 0.0584 mL | 0.2922 mL | 0.5844 mL | 1.4610 mL | |
| 40 mM | 0.0438 mL | 0.2191 mL | 0.4383 mL | 1.0957 mL | |
| 50 mM | 0.0351 mL | 0.1753 mL | 0.3506 mL | 0.8766 mL | |
| 60 mM | 0.0292 mL | 0.1461 mL | 0.2922 mL | 0.7305 mL | |
| 80 mM | 0.0219 mL | 0.1096 mL | 0.2191 mL | 0.5479 mL | |
| 100 mM | 0.0175 mL | 0.0877 mL | 0.1753 mL | 0.4383 mL |