Br-C10-methyl ester
Based on 1 Customer Validation
Br-C10-methyl ester is a PROTAC linker, which refers to the alkyl/ether composition. Br-C10-methyl ester is used in the synthesis of a series of PROTACs (MS432). PROTACs contain two different ligands connected by a linker; one is the VHL ligand portion and the other is for the target protein.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 97.87%
- CAS 番号: 6287-90-7
- 分子式: C12H23BrO2
- 分子量:279.21
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
[1]|
Alkyl/ether |
化学情報
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CAS 番号 6287-90-7
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性状 <12.5°C Solid,>12.5°C Liquid
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分子量 279.21
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分子式 C12H23BrO2
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Color Colorless to light yellow
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SMILES
O=C(OC)CCCCCCCCCCBr
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (358.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (264 KB)
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SDS (393 KB)
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- Deutsch - DE (393 KB)
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- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5815 mL | 17.9077 mL | 35.8153 mL | 89.5383 mL |
| 5 mM | 0.7163 mL | 3.5815 mL | 7.1631 mL | 17.9077 mL | |
| 10 mM | 0.3582 mL | 1.7908 mL | 3.5815 mL | 8.9538 mL | |
| 15 mM | 0.2388 mL | 1.1938 mL | 2.3877 mL | 5.9692 mL | |
| 20 mM | 0.1791 mL | 0.8954 mL | 1.7908 mL | 4.4769 mL | |
| 25 mM | 0.1433 mL | 0.7163 mL | 1.4326 mL | 3.5815 mL | |
| 30 mM | 0.1194 mL | 0.5969 mL | 1.1938 mL | 2.9846 mL | |
| 40 mM | 0.0895 mL | 0.4477 mL | 0.8954 mL | 2.2385 mL | |
| 50 mM | 0.0716 mL | 0.3582 mL | 0.7163 mL | 1.7908 mL | |
| 60 mM | 0.0597 mL | 0.2985 mL | 0.5969 mL | 1.4923 mL | |
| 80 mM | 0.0448 mL | 0.2238 mL | 0.4477 mL | 1.1192 mL | |
| 100 mM | 0.0358 mL | 0.1791 mL | 0.3582 mL | 0.8954 mL |