BTCy
BTCy is a near-infrared (NIR) fluorescence probe with polarity-responsive and cell plasma membrane-targeting properties. BTCy can be used for in vivo imaging of tumor tissue (λex = 561 nm, λem = 600-700 nm).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C28H25BrN2OS2
- 分子量:549.54
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
BTCy (0-50 μM; 24 h) has low cytotoxicity and is biocompatible for living cells[1].
BTCy exhibits good fluorescence stability and is able to detect the polarity change selectively[1].
BTCy (10 μM) stains HeLa and HepG2 cells. The cell plasma membrane is specifically and strongly lit up after being stained for 0.5–5 h. The fluorescence intensity of BTCy on the cell plasma membrane shows slight reduction after 2 h[1].
BTCy (0.1-10 μM; 30 min) stain shows specific fluorescence on the cell plasma membrane even at a low concentration at 100 nM in HeLa cells[1].
BTCy (0.1-10 μM; 30 min) can be used for monitoring cell plasma membrane polarity variation during the ferroptosis process[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 549.54
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分子式 C28H25BrN2OS2
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SMILES
CCN1C2=C(S/C1=C\C=C3C=CC(C(/C=C/C4=[N+](C5=C(S4)C=CC=C5)CC)=C/3)=O)C=CC=C2.[Br-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)