Caloxin 1C2
Based on 1 Customer Validation
Caloxin 1C2 is a specific PMCA (plasma-membrane Ca2+-ATPases) inhibitor. Caloxin 1C2 is selective for PMCA4 over PMCA1, 2 and 3. The Ki values of Caloxin 1C2 are 2.3 μM for PMCA4 and 21 μM for PMCA1. Caloxin 1C2 dose not cause any significant effects on total Ca2+ transfer. Caloxin 1C2 affects coronary contractility.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.47%
- 分子式: C80H134N26O24
- 分子量:1844.08
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Calcium Channel アイソフォーム固有の製品をすべて表示
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生物活性
Ki: 2.3±0.3 μM (PMCA4), 21±6 μM (PMCA1)[2]
化学情報
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性状 Solid
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分子量 1844.08
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分子式 C80H134N26O24
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Color White to off-white
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配列
Thr-Ala-Trp-Ser-Glu-Val-Leu-Asp-Leu-Leu-Arg-Arg-Gly-Gly-Gly-Ser-Lys-NH2
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シーケンスの短縮
TAWSEVLDLLRRGGGSK-NH2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 100 mg/mL (54.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Sillanpää JK, et al. Calcium transfer across the outer mantle epithelium in the Pacific oyster, Crassostrea gigas. Proc Biol Sci. 2018 Nov 14;285(1891):20181676. [Content Brief]
[2]. Pande J, et al. Functional effects of caloxin 1c2, a novel engineered selective inhibitor of plasma membrane Ca(2+)-pump isoform 4, on coronary artery. J Cell Mol Med. 2008 Jun;12(3):1049-60. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5423 mL | 2.7114 mL | 5.4228 mL | 13.5569 mL |
| 5 mM | 0.1085 mL | 0.5423 mL | 1.0846 mL | 2.7114 mL | |
| 10 mM | 0.0542 mL | 0.2711 mL | 0.5423 mL | 1.3557 mL | |
| 15 mM | 0.0362 mL | 0.1808 mL | 0.3615 mL | 0.9038 mL | |
| 20 mM | 0.0271 mL | 0.1356 mL | 0.2711 mL | 0.6778 mL | |
| 25 mM | 0.0217 mL | 0.1085 mL | 0.2169 mL | 0.5423 mL | |
| 30 mM | 0.0181 mL | 0.0904 mL | 0.1808 mL | 0.4519 mL | |
| 40 mM | 0.0136 mL | 0.0678 mL | 0.1356 mL | 0.3389 mL | |
| 50 mM | 0.0108 mL | 0.0542 mL | 0.1085 mL | 0.2711 mL |
Caloxin 1C2 関連分類
HY-P10655 関連分類
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