CDN-A
CDN-A is a cyclic di-nucleotide, it can be used to synthesis antibody-drug conjugate (ADC). Cyclic di-nucleotides are potent stimulators of innate and adaptive immune responses. In humans, cyclic di-nucleotide, which are either produced endogenously in response to foreign DNA or by invading bacterial pathogens, trigger the innate immune system by activating the expression of interferon genes.
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- CAS 番号: 2586047-09-6
- 分子式: C22H29N11O12P2
- 分子量:701.48
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
化学情報
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CAS 番号 2586047-09-6
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分子量 701.48
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分子式 C22H29N11O12P2
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SMILES
O=P(O)(O[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N)=NC=N3)O[C@@H]1COP4(O)=O)OC[C@@H](O5)[C@@H](CCN)[C@@H](O4)[C@@H]5N6C=NC7=C6N=C(N)NC7=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[2]. Lirussi D, et al. Type I IFN and not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation Pathway. EBioMedicine. 2017 Aug;22:100-111. [Content Brief]
[3]. Schaap P. Cyclic di-nucleotide signaling enters the eukaryote domain. IUBMB Life. 2013 Nov;65(11):897-903. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CDN-A 関連分類
HY-148420 関連分類
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