CFM-4
Based on 1 Customer Validation
CFM-4 is a potent small molecular antagonist of CARP-1/APC-2 binding. CFM-4 prevents CARP-1 binding with APC-2, causes G2M cell cycle arrest, and induces apoptosis with an IC50 range of 10-15 μM. CFM-4 also suppresses growth of drug-resistant human breast cancer cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.85%
- CAS 番号: 331458-02-7
- 分子式: C22H16ClN3OS
- 分子量:405.90
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
化学情報
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CAS 番号 331458-02-7
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性状 Solid
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分子量 405.90
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分子式 C22H16ClN3OS
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Color Light yellow to yellow
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SMILES
O=C1N(CC2=CC=CC=C2Cl)C3=C(C=CC=C3)C14SC(C5=CC=CC=C5)=NN4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 25 mg/mL (61.59 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4637 mL | 12.3183 mL | 24.6366 mL | 61.5915 mL |
| 5 mM | 0.4927 mL | 2.4637 mL | 4.9273 mL | 12.3183 mL | |
| 10 mM | 0.2464 mL | 1.2318 mL | 2.4637 mL | 6.1592 mL | |
| 15 mM | 0.1642 mL | 0.8212 mL | 1.6424 mL | 4.1061 mL | |
| 20 mM | 0.1232 mL | 0.6159 mL | 1.2318 mL | 3.0796 mL | |
| 25 mM | 0.0985 mL | 0.4927 mL | 0.9855 mL | 2.4637 mL | |
| 30 mM | 0.0821 mL | 0.4106 mL | 0.8212 mL | 2.0531 mL | |
| 40 mM | 0.0616 mL | 0.3080 mL | 0.6159 mL | 1.5398 mL | |
| 50 mM | 0.0493 mL | 0.2464 mL | 0.4927 mL | 1.2318 mL | |
| 60 mM | 0.0411 mL | 0.2053 mL | 0.4106 mL | 1.0265 mL |