Chlorthalidone impurity
Based on 1 Customer Validation
Chlorthalidone impurity (Compound Impurity B) is an impurity of Chlorthalidone (HY-15833). Chlorthalidone is a type of thiazide-like diuretic and is used for the study of hypertension.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.68%
- CAS 番号: 5270-74-6
- 分子式: C14H10ClNO5S
- 分子量:339.75
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
体外実験
化学情報
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CAS 番号 5270-74-6
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性状 Solid
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分子量 339.75
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分子式 C14H10ClNO5S
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Color White to off-white
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SMILES
O=C(O)C1=CC=CC=C1C(C2=CC=C(Cl)C(S(=O)(N)=O)=C2)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 125 mg/mL (367.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (285 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Bauer J, et al. Stability-indicating assay for chlorthalidone formulation: evaluation of the USP analysis and a high-performance liquid chromatographic analysis. J Pharm Sci. 1983 Aug;72(8):924-8. [Content Brief]
[2]. Barrios V, et al. Which thiazide to choose as add-on therapy for hypertension? Integr Blood Press Control. 2014 Jul 30;7:35-47. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9433 mL | 14.7167 mL | 29.4334 mL | 73.5835 mL |
| 5 mM | 0.5887 mL | 2.9433 mL | 5.8867 mL | 14.7167 mL | |
| 10 mM | 0.2943 mL | 1.4717 mL | 2.9433 mL | 7.3584 mL | |
| 15 mM | 0.1962 mL | 0.9811 mL | 1.9622 mL | 4.9056 mL | |
| 20 mM | 0.1472 mL | 0.7358 mL | 1.4717 mL | 3.6792 mL | |
| 25 mM | 0.1177 mL | 0.5887 mL | 1.1773 mL | 2.9433 mL | |
| 30 mM | 0.0981 mL | 0.4906 mL | 0.9811 mL | 2.4528 mL | |
| 40 mM | 0.0736 mL | 0.3679 mL | 0.7358 mL | 1.8396 mL | |
| 50 mM | 0.0589 mL | 0.2943 mL | 0.5887 mL | 1.4717 mL | |
| 60 mM | 0.0491 mL | 0.2453 mL | 0.4906 mL | 1.2264 mL | |
| 80 mM | 0.0368 mL | 0.1840 mL | 0.3679 mL | 0.9198 mL | |
| 100 mM | 0.0294 mL | 0.1472 mL | 0.2943 mL | 0.7358 mL |