Chol-PEG
Chol-PEG is an amphiphilic cholesterol-polyethylene glycol conjugate and also a liposomelike surface modifier. After Chol-PEG is incorporated into liposomelike vesicles, it forms a hydrophilic barrier on their surface, increases the thickness of the bound water layer around the liposomelike vesicles, and enhances the release rate of encapsulated compounds. Chol-PEG can be used as a modifier to prepare nonionic surfactant vesicles (liposomelike vesicles) for drug delivery applications.
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- CAS 番号: 27321-96-6
- 分子式: C29H50O2
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Chol-PEG can form Chol-PEGm, which is used to modify nimodipine (HY-B0265)-loaded vesicles. As the molecular weight of PEG increases, the vesicle size increases, zeta potential decreases, and FALT increases; the release rate of nimodipine increases with the increase in PEG molecular weight; among these, vesicles modified with Chol-PEG10,000 show the highest cumulative release within 24 h, reaching up to 43.86%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 27321-96-6
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分子式 C29H50O2
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SMILES
OCCOC1CC2=CCC3C(C2(CC1)C)CCC4(C(C(CCCC(C)C)C)CCC34)C.[n]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Chol-PEG 関連分類
HY-144007 関連分類
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