CK2-IN-3
CK2-IN-3 is a selective and potent CK2 inhibitor (Kd: 12 nM), with IC50 values of 1.51 μM (CK2α) and 7.64 μM (CK2α’). CK2-IN-3 can be used in the research of cancers.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2969205-85-2
- 分子式: C22H26N4O7
- 分子量:458.46
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
CK2α 1.51 μM (IC50) |
CK2α' 7.64 μM (IC50) |
CK2-IN-3 (compound 31, 1 nM-100 μM) inhibits CK2 activities in permeabilized cells, with IC50 values of 8 nM (CK2α) and 38 nM (CK2α’)[1].
CK2-IN-3 (10 µM, 48 h) shows no significant cytotoxicity across 60 cancer cell lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 2969205-85-2
-
分子量 458.46
-
分子式 C22H26N4O7
-
SMILES
O=C(O)C1=CC=C(C2=C3N=C(N(C(OC(C)(C)C)=O)CCOCCO)C=CN3N=C2)C=C1O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)