Complement factor D-IN-2
Based on 1 Customer Validation
Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. Complement factor D-IN-2 can be used for the research of autoimmune diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.33%
- CAS 番号: 1903742-34-6
- 分子式: C27H24BrN7O3
- 分子量:574.43
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
生物活性
complement factor D[1]
化学情報
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CAS 番号 1903742-34-6
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性状 Solid
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分子量 574.43
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分子式 C27H24BrN7O3
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Color White to off-white
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SMILES
O=C([C@H]1N(C(CN2N=C(C(C)=O)C3=C2C=CC(C4=CN=C(C)N=C4)=C3)=O)[C@]5([H])C[C@]5([H])C1)NC6=NC(Br)=CC=C6
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 100 mg/mL (174.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7409 mL | 8.7043 mL | 17.4086 mL | 43.5214 mL |
| 5 mM | 0.3482 mL | 1.7409 mL | 3.4817 mL | 8.7043 mL | |
| 10 mM | 0.1741 mL | 0.8704 mL | 1.7409 mL | 4.3521 mL | |
| 15 mM | 0.1161 mL | 0.5803 mL | 1.1606 mL | 2.9014 mL | |
| 20 mM | 0.0870 mL | 0.4352 mL | 0.8704 mL | 2.1761 mL | |
| 25 mM | 0.0696 mL | 0.3482 mL | 0.6963 mL | 1.7409 mL | |
| 30 mM | 0.0580 mL | 0.2901 mL | 0.5803 mL | 1.4507 mL | |
| 40 mM | 0.0435 mL | 0.2176 mL | 0.4352 mL | 1.0880 mL | |
| 50 mM | 0.0348 mL | 0.1741 mL | 0.3482 mL | 0.8704 mL | |
| 60 mM | 0.0290 mL | 0.1451 mL | 0.2901 mL | 0.7254 mL | |
| 80 mM | 0.0218 mL | 0.1088 mL | 0.2176 mL | 0.5440 mL | |
| 100 mM | 0.0174 mL | 0.0870 mL | 0.1741 mL | 0.4352 mL |