DB772 free base
Based on 1 publication(s) in Google Scholar
DB772 free base is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 free base also has anti-prion activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 433735-90-1
- 分子式: C20H16N4O
- 分子量:328.37
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
MedChemExpress(MCE)の使用を引用している文献 DB772 free base
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
8.6 μM
Compound: DB772
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Drug concentration required to inhibit B16 cell growth by 50% after 72 hours of incubation
Drug concentration required to inhibit B16 cell growth by 50% after 72 hours of incubation
|
[PMID: 11985467] |
化学情報
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CAS 番号 433735-90-1
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分子量 328.37
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分子式 C20H16N4O
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SMILES
C1(N=C(C2=CC=C(C3=CC=C(C4=NCCN4)C=C3)O2)N5)=C5C=CC=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
純度とドキュメンテーション
参考文献
[1]. James B Stanton, et al. Discovery of a novel, monocationic, small-molecule inhibitor of scrapie prion accumulation in cultured sheep microglia and Rov cells. PLoS One. 2012;7(11):e51173. [Content Brief]
[2]. Benjamin W Newcomer, et al. Efficacy of an antiviral compound to inhibit replication of multiple pestivirus species. Antiviral Res. 2012 Nov;96(2):127-9. [Content Brief]
[3]. Kelcey D Dinkel, et al. Antiprion Activity of DB772 and Related Monothiophene- and Furan-Based Analogs in a Persistently Infected Ovine Microglia Culture System. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5467-82. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)