DBCO-PEG13-DBCO
Based on 1 Customer Validation
DBCO-PEG13-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG13-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.24%
- 分子式: C66H86N4O17
- 分子量:1207.41
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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性状 Oil
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分子量 1207.41
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分子式 C66H86N4O17
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Color Colorless to light yellow
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SMILES
O=C(NCCC(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(NCCC(N4C5=CC=CC=C5C#CC6=CC=CC=C6C4)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 100 mg/mL (82.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8282 mL | 4.1411 mL | 8.2822 mL | 20.7055 mL |
| 5 mM | 0.1656 mL | 0.8282 mL | 1.6564 mL | 4.1411 mL | |
| 10 mM | 0.0828 mL | 0.4141 mL | 0.8282 mL | 2.0705 mL | |
| 15 mM | 0.0552 mL | 0.2761 mL | 0.5521 mL | 1.3804 mL | |
| 20 mM | 0.0414 mL | 0.2071 mL | 0.4141 mL | 1.0353 mL | |
| 25 mM | 0.0331 mL | 0.1656 mL | 0.3313 mL | 0.8282 mL | |
| 30 mM | 0.0276 mL | 0.1380 mL | 0.2761 mL | 0.6902 mL | |
| 40 mM | 0.0207 mL | 0.1035 mL | 0.2071 mL | 0.5176 mL | |
| 50 mM | 0.0166 mL | 0.0828 mL | 0.1656 mL | 0.4141 mL | |
| 60 mM | 0.0138 mL | 0.0690 mL | 0.1380 mL | 0.3451 mL | |
| 80 mM | 0.0104 mL | 0.0518 mL | 0.1035 mL | 0.2588 mL |
DBCO-PEG13-DBCO 関連分類
HY-140305 関連分類
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