DBCO-PEG4-PFP ester
Based on 1 Customer Validation
DBCO-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG4-PFP ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.0%
- 分子式: C36H35F5N2O8
- 分子量:718.66
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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性状 Oil
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分子量 718.66
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分子式 C36H35F5N2O8
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Color Colorless to light yellow
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SMILES
O=C(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)CCC(NCCOCCOCCOCCOCCC(OC4=C(C(F)=C(C(F)=C4F)F)F)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 100 mg/mL (139.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3915 mL | 6.9574 mL | 13.9148 mL | 34.7870 mL |
| 5 mM | 0.2783 mL | 1.3915 mL | 2.7830 mL | 6.9574 mL | |
| 10 mM | 0.1391 mL | 0.6957 mL | 1.3915 mL | 3.4787 mL | |
| 15 mM | 0.0928 mL | 0.4638 mL | 0.9277 mL | 2.3191 mL | |
| 20 mM | 0.0696 mL | 0.3479 mL | 0.6957 mL | 1.7393 mL | |
| 25 mM | 0.0557 mL | 0.2783 mL | 0.5566 mL | 1.3915 mL | |
| 30 mM | 0.0464 mL | 0.2319 mL | 0.4638 mL | 1.1596 mL | |
| 40 mM | 0.0348 mL | 0.1739 mL | 0.3479 mL | 0.8697 mL | |
| 50 mM | 0.0278 mL | 0.1391 mL | 0.2783 mL | 0.6957 mL | |
| 60 mM | 0.0232 mL | 0.1160 mL | 0.2319 mL | 0.5798 mL | |
| 80 mM | 0.0174 mL | 0.0870 mL | 0.1739 mL | 0.4348 mL | |
| 100 mM | 0.0139 mL | 0.0696 mL | 0.1391 mL | 0.3479 mL |
DBCO-PEG4-PFP ester 関連分類
HY-140278 関連分類
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