DBM-MMAF
Based on 2 publication(s) in Google Scholar
DBM-MMAF is a agent-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody agent conjugate (ADC).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.65%
- CAS 番号: 1810001-93-4
- 分子式: C49H74Br2N6O11
- 分子量:1082.95
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 DBM-MMAF
MoreDrug-Linker Conjugates for ADC アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
[1]|
Auristatin |
体外実験
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1810001-93-4
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性状 Solid
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分子量 1082.95
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分子式 C49H74Br2N6O11
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Color Off-white to light yellow
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SMILES
C[C@@H](C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(CCCCCN(C3=O)C(C(Br)=C3Br)=O)=O)=O)=O)=O)OC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
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Journal Impact Factor
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Most Recent
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Cells
2023 Sep 30;12(19):2393. PMID: 37830607
溶剤 & 溶解度
体外:
DMSO : 200 mg/mL (184.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9234 mL | 4.6170 mL | 9.2340 mL | 23.0851 mL |
| 5 mM | 0.1847 mL | 0.9234 mL | 1.8468 mL | 4.6170 mL | |
| 10 mM | 0.0923 mL | 0.4617 mL | 0.9234 mL | 2.3085 mL | |
| 15 mM | 0.0616 mL | 0.3078 mL | 0.6156 mL | 1.5390 mL | |
| 20 mM | 0.0462 mL | 0.2309 mL | 0.4617 mL | 1.1543 mL | |
| 25 mM | 0.0369 mL | 0.1847 mL | 0.3694 mL | 0.9234 mL | |
| 30 mM | 0.0308 mL | 0.1539 mL | 0.3078 mL | 0.7695 mL | |
| 40 mM | 0.0231 mL | 0.1154 mL | 0.2309 mL | 0.5771 mL | |
| 50 mM | 0.0185 mL | 0.0923 mL | 0.1847 mL | 0.4617 mL | |
| 60 mM | 0.0154 mL | 0.0770 mL | 0.1539 mL | 0.3848 mL | |
| 80 mM | 0.0115 mL | 0.0577 mL | 0.1154 mL | 0.2886 mL | |
| 100 mM | 0.0092 mL | 0.0462 mL | 0.0923 mL | 0.2309 mL |
DBM-MMAF 関連分類
HY-136287 関連分類
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