DCOIT (Standard)
DCOIT (Standard) (Kathon 930 (Standard)) is the analytical standard of DCOIT (HY-W041308). This product is intended for research and analytical applications. DCOIT (Kathon 930) is an isothiazolinone biocide and environmental pollutant that directly binds to G protein α subunits, with KD values of 0.92 mM and 0.4 mM for Gαs and Gαi, respectively. Binding of DCOIT to Gαi enhances the interaction between Gαi and mitochondrial calcium uniporter (MCU), alters the subcellular distribution of intracellular Ca2+, and activates PKC/MEK/ERK signaling. DCOIT upregulates CYP19a transcription and aromatase activity, thereby disrupting steroid hormone homeostasis. DCOIT is used in studies of reproductive endocrine disruption and environmental toxicology.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98%
- CAS 番号: 64359-81-5
- 分子式: C11H17Cl2NOS
- 分子量:282.23
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
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HY-W041308
DCOITIsothiazolinone -
HY-I0144
ThiazolidineHeterocyclic Compound -
HY-P0009A
Cetrorelix acetateGnRH Receptor Antagonist -
HY-14789
(R)-ElagolixGnRH Receptor Antagonist -
HY-P0051
LecirelinGnRH Analogue -
HY-130249
BAY-298LH-R Antagonist -
HY-P0056A
Histrelin acetateGnRH Receptor Agonist -
HY-P0243
Luteinizing Hormone Releasing Hormone (LH-RH), salmonLuteinizing Hormone-releasing Hormone -
HY-P0053
FertirelinGnRH Analog -
HY-P1808
LGnRH-III, lampreyGnRH Agonist -
HY-125611
Fluorogestone acetateProgesterone -
HY-14789R
(R)-Elagolix (Standard)GnRH Receptor Antagonist
Product Information
説明
アプリケーション
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 64359-81-5
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分子量 282.23
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分子式 C11H17Cl2NOS
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SMILES
O=C1N(CCCCCCCC)SC(Cl)=C1Cl
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別名
Kathon 930 (Standard)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DCOIT (Standard) 関連分類
HY-W041308R 関連分類
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Keywords
- DCOIT (Standard)
- 64359-81-5
- Kathon 930 (Standard)
- Reference Standards
- Environmental Pollutants
- GnRH Receptor
- H295R cells
- hypothalamus-pituitary-gonadal axis
- Gαi
- isothiazolinone biocide
- blood-brain barrier permeability
- mitochondrial calcium uniporter
- reproductive endocrine disruption
- marine medaka
- MAPK pathway
- O. melastigma
- Inhibitor
- inhibitor
- inhibit