Dehydrochenodeoxycholic acid
Based on 1 Customer Validation
Dehydrochenodeoxycholic acid is a ketone bile acid.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.97%
- CAS 番号: 859-97-2
- 分子式: C24H36O4
- 分子量:388.54
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
10.93 μM
Compound: 29
|
Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assay
Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assay
|
[PMID: 25735208] |
化学情報
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CAS 番号 859-97-2
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性状 Solid
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分子量 388.54
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分子式 C24H36O4
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Color White to off-white
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SMILES
O=C1C[C@@]([H])(CC([C@@]2([C@@]3(CC[C@]4([C@]2(CC[C@@]4([C@@H](CCC(O)=O)C)[H])[H])C)[H])[H])=O)[C@]3(C)CC1
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別名
5β-Cholanic acid-3,7-dione; 3,7-Dioxo-5β-cholanoic acid; 3,7-Diketochenodeoxycholic acid
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (257.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5737 mL | 12.8687 mL | 25.7374 mL | 64.3434 mL |
| 5 mM | 0.5147 mL | 2.5737 mL | 5.1475 mL | 12.8687 mL | |
| 10 mM | 0.2574 mL | 1.2869 mL | 2.5737 mL | 6.4343 mL | |
| 15 mM | 0.1716 mL | 0.8579 mL | 1.7158 mL | 4.2896 mL | |
| 20 mM | 0.1287 mL | 0.6434 mL | 1.2869 mL | 3.2172 mL | |
| 25 mM | 0.1029 mL | 0.5147 mL | 1.0295 mL | 2.5737 mL | |
| 30 mM | 0.0858 mL | 0.4290 mL | 0.8579 mL | 2.1448 mL | |
| 40 mM | 0.0643 mL | 0.3217 mL | 0.6434 mL | 1.6086 mL | |
| 50 mM | 0.0515 mL | 0.2574 mL | 0.5147 mL | 1.2869 mL | |
| 60 mM | 0.0429 mL | 0.2145 mL | 0.4290 mL | 1.0724 mL | |
| 80 mM | 0.0322 mL | 0.1609 mL | 0.3217 mL | 0.8043 mL | |
| 100 mM | 0.0257 mL | 0.1287 mL | 0.2574 mL | 0.6434 mL |