Dibromoacetaldehyde
Dibromoacetaldehyde, a halogenated product, is a byproduct in drinking water and has genotoxicity.
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- CAS 番号: 3039-13-2
- 分子式: C2H2Br2O
- 分子量:201.84
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
The rank order of HAL cytotoxicity is tribromoacetaldehyde (TBAL)≈chloroacetaldehyde (CAL)>dibromoacetaldehyde (DBAL)≈bromochloroacetaldehyde (BCAL)≈ dibromochloroacetaldehyde (DBCAL)>IAL>bromoacetaldehyde (BAL)≈ bromodichloroacetaldehyde (BDCAL)>dichloroacetaldehyde (DCAL)> trichloroacetaldehyde (TCAL). The HALs were highly cytotoxic compared to other DBP chemical classes. The rank order of HAL genotoxicity is DBAL>CAL≈DBCAL>TBAL≈BAL>BDCAL>BCAL≈DCAL>IAL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
化学情報
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CAS 番号 3039-13-2
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分子量 201.84
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分子式 C2H2Br2O
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SMILES
O=CC(Br)Br
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
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Genotoxicity/Mutagenicity Study
The bacterial reverse mutation assay detects point mutations that restore amino-acid prototrophy in auxotrophic Salmonella typhimurium or Escherichia coli tester strains; after exposure to a test article, mutagenic activity is read out as an increased number of revertant colonies on minimal agar compared with the vehicle control. The assay uses tester strains with different mutation targets so that base-substitution and frameshift mutagens can be detected, and testing is performed with and without exogenous mammalian metabolic activation because some chemicals require biotransformation to become mutagenic.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)