Diosbulbin D
Diosbulbin D is a potential hepatotoxic compound that can be isolated from Dioscorea bulbifera L.. Diosbulbin D induces apoptosis in L-02 cells.
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- CAS 番号: 66756-57-8
- 分子式: C19H20O6
- 分子量:344.36
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Diosbulbin D (10-80 μM; 12-72 h) can induce cytotoxicity in human normal liver L-02 cells[1].
Diosbulbin D (40 μM; 24 h) induces morphological changes in L-02 cells[1].
Diosbulbin D (20-80 μM; 12-48 h) induces L-02 cells apoptosis in a time- and concentration-dependent manner[1].
Diosbulbin D (20-80 μM; 24 h) induces activation of caspase 3 in L-02 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:L-02 cells
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Concentration:10, 20, 40 and 80 μM
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Incubation Time:12, 24, 48 and 72 h
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Result:Decreased L-02 cells viability in a concentration- and time-dependent manner.
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Cell Line:L-02 cells
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Concentration:20, 40 and 80 μM
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Incubation Time:12, 24 and 48 h
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Result:Induced apoptosis in a time- and concentration-dependent manner.
化学情報
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CAS 番号 66756-57-8
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分子量 344.36
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分子式 C19H20O6
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SMILES
CC12C3C(C(CC1C(OC(C4=COC=C4)C2)=O)=O)C5CC(OC5=O)C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)