Disomotide
Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma.
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- CAS 番号: 181477-43-0
- 分子式: C47H74N10O14S
- 分子量:1035.21
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
For Ag activation, PBMCs from immunized patients are cultured for 6 days with Disomotide (G209-2M) peptide (1 μM)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 181477-43-0
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分子量 1035.21
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分子式 C47H74N10O14S
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別名
G209-2M; GP100:209-217(210M); MPS-22
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配列
Ile-Met-Asp-Gln-Val-Pro-Phe-Ser-Val
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シーケンスの短縮
IMDQVPFSV
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Yang S, et al. Antimelanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity. J Immunol. 2002 Jul 1;169(1):531-9. [Content Brief]
[2]. Ahmadzadeh M, et al. IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells. J Immunother. 2007 Apr;30(3):294-302. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)