DOPE-NHS
Based on 1 Customer Validation
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 92.0%
- CAS 番号: 1010188-79-0
- 分子式: C50H87N2O13P
- 分子量:955.21
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保管条件:
RT, sealed storage, away from moisture and light.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
The use of DOPE-NHS allows for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles[1].
MSC derived exosomes are conjugated with rabies viral glycoprotein through a DOPE-NHS linker[1].
Exosomes are conjugated with cardiac homing peptide through a DOPE-NHS linker[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1010188-79-0
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性状 Oil
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分子量 955.21
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分子式 C50H87N2O13P
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Color Colorless to off-white
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SMILES
CCCCCCCC/C=C\CCCCCCCC(OC[C@@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COP(OCCNC(CCCC(ON1C(CCC1=O)=O)=O)=O)(O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
RT, sealed storage, away from moisture and light
In solvent -80°C 1 year -20°C 6 months
溶剤 & 溶解度
DMSO : 25 mg/mL (26.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Cui GH, et al. RVG-modified exosomes derived from mesenchymal stem cells rescue memory deficits by regulating inflammatory responses in a mouse model of Alzheimer's disease. Immun Ageing. 2019 May 13;16:10. [Content Brief]
[2]. Vandergriff A, et al. Targeting regenerative exosomes to myocardial infarction using cardiac homing peptide. Theranostics. 2018 Feb 14;8(7):1869-1878. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0469 mL | 5.2345 mL | 10.4689 mL | 26.1723 mL |
| 5 mM | 0.2094 mL | 1.0469 mL | 2.0938 mL | 5.2345 mL | |
| 10 mM | 0.1047 mL | 0.5234 mL | 1.0469 mL | 2.6172 mL | |
| 15 mM | 0.0698 mL | 0.3490 mL | 0.6979 mL | 1.7448 mL | |
| 20 mM | 0.0523 mL | 0.2617 mL | 0.5234 mL | 1.3086 mL | |
| 25 mM | 0.0419 mL | 0.2094 mL | 0.4188 mL | 1.0469 mL |
DOPE-NHS 関連分類
HY-150241 関連分類
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