DOPE-PEG2000-PTP
DOPE-PEG2000-PTP (DOPE-PEG2000-Mal-Cys-KTLLPTP) is an amphiphilic lipid-PEG-peptide conjugate consisting of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the PTP (pancreatic cancer-targeting peptide). DOPE-PEG2000-PTP is used for pancreatic cancer-targeted drug delivery through liposome and nanoparticle functionalization.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
-
Help & FAQs
生物活性
DOPE-PEG2000-PTP: surface decoration of liposomes and lipid nanoparticles for pancreatic cancer-targeted drug delivery, enabling selective drug accumulation in pancreatic tumor tissues.
Structural composition:
(1) DOPE; a fusogenic phospholipid with two oleoyl chains that anchors into lipid bilayers and promotes pH-dependent membrane fusion for intracellular drug release;
(2) PEG2000; a hydrophilic polymer that provides steric stabilization, reduces opsonization and immune clearance, and extends circulation half-life;
(3) PTP peptide; a pancreatic cancer-targeting peptide that specifically binds to receptors or surface markers overexpressed on pancreatic cancer cells, directing nanocarriers to pancreatic tumor tissues for enhanced drug uptake and improved therapeutic efficacy with reduced systemic toxicity.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
SMILES
[DOPE-PEG2000-PTP]
-
別名
DOPE-PEG2000-Mal-Cys-KTLLPTP
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DOPE-PEG2000-PTP 関連分類
HY-187403A 関連分類
Powered by Bioz