Disuccinimidyl glutarate
Based on 5 publication(s) in Google Scholar
DSG Crosslinker is an amine-reactive and noncleavable protein crosslinker. DSG Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 79642-50-5
- 分子式: C13H14N2O8
- 分子量:326.26
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
MedChemExpress(MCE)の使用を引用している文献 DSG Crosslinker
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生物活性
化学情報
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CAS 番号 79642-50-5
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性状 Solid
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分子量 326.26
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分子式 C13H14N2O8
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Color Off-white to gray
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SMILES
O=C(CCCC(ON1C(CCC1=O)=O)=O)ON2C(CCC2=O)=O
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別名
DSG Crosslinker; グルタル酸N,N'-ジスクシンイミジル
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (5)
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Journal Impact Factor
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Most Recent
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Nat Commun
2026 Feb 20;17(1):2963. PMID: 41720774 -
Adv Sci (Weinh)
Dimer-Specific FokT-seq Reveals DNA-Binding Dimerization and Novel Genomic Targets of TDP-43. [Abstract]2025 Aug 23:e08902. PMID: 40847753
DSG Crosslinker purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 23:e08902. [Abstract]
DSG Crosslinker (0-400 μM; 10 min). Crosslinking of 3×FLAG‐TDP‐43 in 293T cells with increasing concentrations of DSG shows an increase in the dimeric form and a decrease in the monomeric form. GAPDH was used as the loading control.
DSG Crosslinker purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 23:e08902. [Abstract]
DSG Crosslinker (100 μM; 10 min). Overexpression of 3×FLAG‐TDP‐43, 3×FLAG‐NLS‐FokI, 3×FLAG‐NLS‐FokT, and 3×FLAG‐NLS‐FokTN6A plasmids in 293T cells followed by crosslinking with 100 µM DSG. Western blot analysis was performed to examine their dimerization.
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Genome Biol
DNA G-quadruplex profiling in skeletal muscle stem cells reveals functional and mechanistic insights. [Abstract]2025 Sep 5;26(1):269. PMID: 40913227 -
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溶剤 & 溶解度
DMSO : 100 mg/mL (306.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (247 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0650 mL | 15.3252 mL | 30.6504 mL | 76.6260 mL |
| 5 mM | 0.6130 mL | 3.0650 mL | 6.1301 mL | 15.3252 mL | |
| 10 mM | 0.3065 mL | 1.5325 mL | 3.0650 mL | 7.6626 mL | |
| 15 mM | 0.2043 mL | 1.0217 mL | 2.0434 mL | 5.1084 mL | |
| 20 mM | 0.1533 mL | 0.7663 mL | 1.5325 mL | 3.8313 mL | |
| 25 mM | 0.1226 mL | 0.6130 mL | 1.2260 mL | 3.0650 mL | |
| 30 mM | 0.1022 mL | 0.5108 mL | 1.0217 mL | 2.5542 mL | |
| 40 mM | 0.0766 mL | 0.3831 mL | 0.7663 mL | 1.9157 mL | |
| 50 mM | 0.0613 mL | 0.3065 mL | 0.6130 mL | 1.5325 mL | |
| 60 mM | 0.0511 mL | 0.2554 mL | 0.5108 mL | 1.2771 mL | |
| 80 mM | 0.0383 mL | 0.1916 mL | 0.3831 mL | 0.9578 mL | |
| 100 mM | 0.0307 mL | 0.1533 mL | 0.3065 mL | 0.7663 mL |