EA-230
Based on 1 Customer Validation
EA-230 is a synthetic oligopeptide originally derived from beta-human chorionic gonadotropin (beta-hCG) lysates. EA-230 has anti-inflammatory effects and can be used for the research of sepsis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.27%
- CAS 番号: 503844-09-5
- 分子式: C15H27N5O6
- 分子量:373.40
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male C57Bl/6 mice, ischemia reperfusion injury model[1]
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Dosage:20, 30, 40 or 50 mg/kg
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Administration:Intraperitoneal injection, twice daily for four consecutive days
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Result:Improved survival markedly. With doses between 30–50 mg/kg survival reached 56–62%, the low dose treatment with 20 mg/kg did not have a beneficial effect. Significantly increased renal blood flow (RBF), attenuated CTGF up-regulation, enhanced tubular epithelial cell regeneration and attenuated TGF-beta activation.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 503844-09-5
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性状 Solid
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分子量 373.40
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分子式 C15H27N5O6
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Color White to off-white
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シーケンスの短縮
AQGV
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 125 mg/mL (334.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6781 mL | 13.3905 mL | 26.7809 mL | 66.9523 mL |
| 5 mM | 0.5356 mL | 2.6781 mL | 5.3562 mL | 13.3905 mL | |
| 10 mM | 0.2678 mL | 1.3390 mL | 2.6781 mL | 6.6952 mL | |
| 15 mM | 0.1785 mL | 0.8927 mL | 1.7854 mL | 4.4635 mL | |
| 20 mM | 0.1339 mL | 0.6695 mL | 1.3390 mL | 3.3476 mL | |
| 25 mM | 0.1071 mL | 0.5356 mL | 1.0712 mL | 2.6781 mL | |
| 30 mM | 0.0893 mL | 0.4463 mL | 0.8927 mL | 2.2317 mL | |
| 40 mM | 0.0670 mL | 0.3348 mL | 0.6695 mL | 1.6738 mL | |
| 50 mM | 0.0536 mL | 0.2678 mL | 0.5356 mL | 1.3390 mL | |
| 60 mM | 0.0446 mL | 0.2232 mL | 0.4463 mL | 1.1159 mL | |
| 80 mM | 0.0335 mL | 0.1674 mL | 0.3348 mL | 0.8369 mL | |
| 100 mM | 0.0268 mL | 0.1339 mL | 0.2678 mL | 0.6695 mL |
EA-230 関連分類
HY-106279 関連分類
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