eIF4E-IN-2
Based on 1 Customer Validation
eIF4E-IN-2 is a potent inhibitor of eukaryotic initiation factor 4e (eIF4e) with an IC50 of 13 nM. eIF4E-IN-2 inhibits MDA-MB-361 cells proliferation. eIF4E-IN-2 can be used for the study of breast cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.91%
- CAS 番号: 2575840-38-7
- 分子式: C37H33ClF2N8O4S2
- 分子量:791.29
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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eIF4 13 nM () |
eIF4E-IN-2 (Compound 1188) inhibits MDA-MB-361 cells proliferation with an IC50 of 46.8 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2575840-38-7
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性状 Solid
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分子量 791.29
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分子式 C37H33ClF2N8O4S2
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Color Light yellow to yellow
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SMILES
N#CC1=C(N(C2CCN(C3CC(F)(C3)F)CC2)C)N=CC(N=C(C)N4CC#CC5=CC=C(C=C5C6=CC=NC7=C6SC=C7C(NS(=O)(C)=O)=O)Cl)=C1C4=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (63.19 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2638 mL | 6.3188 mL | 12.6376 mL | 31.5940 mL |
| 5 mM | 0.2528 mL | 1.2638 mL | 2.5275 mL | 6.3188 mL | |
| 10 mM | 0.1264 mL | 0.6319 mL | 1.2638 mL | 3.1594 mL | |
| 15 mM | 0.0843 mL | 0.4213 mL | 0.8425 mL | 2.1063 mL | |
| 20 mM | 0.0632 mL | 0.3159 mL | 0.6319 mL | 1.5797 mL | |
| 25 mM | 0.0506 mL | 0.2528 mL | 0.5055 mL | 1.2638 mL | |
| 30 mM | 0.0421 mL | 0.2106 mL | 0.4213 mL | 1.0531 mL | |
| 40 mM | 0.0316 mL | 0.1580 mL | 0.3159 mL | 0.7898 mL | |
| 50 mM | 0.0253 mL | 0.1264 mL | 0.2528 mL | 0.6319 mL | |
| 60 mM | 0.0211 mL | 0.1053 mL | 0.2106 mL | 0.5266 mL |
eIF4E-IN-2 関連分類
HY-145262 関連分類
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