Enristomig
Based on 1 Customer Validation
Enristomig (ES-101) is a multispecific antibody. Enristomig is both a PD-L1 antagonist and a conditional agonist of 4-1BB. Enristomig can be used for research on PD-L1 expressing tumors.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.447%
- CAS 番号: 2539845-73-1
- 分子量:101.884 kDa
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
[G1 VH-VH'-h-CH2-CH3]-dimer
Human
TNFRSF9 & CD274
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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VH-VH'-h-CH2-CH3
ELISA, FACS, Functional assay
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Immobilized 4-1BB/TNFRSF9 Protein, Human (HEK293, His, HY-P70678) can bind Enristomig. The EC50 for this effect is 4.611 ng/mL. -
Immobilized PD-L1 Protein, Human (HEK293, HY-P73361) can bind Enristomig. The EC50 for this effect is 2.063 ng/mL.
化学情報
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CAS 番号 2539845-73-1
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性状 Liquid
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分子量 101.884 kDa
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Color Colorless to light yellow
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SMILES
[Enristomig]
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別名
ES-101; INBRX-105
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輸送条件
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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データシート (253 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
参考文献
[1]. Enristomig
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)