EPZ020809
EPZ020809 is a competitive KDM4C inhibitor with a Ki of 31 nM.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1503332-97-5
- 分子式: C10H8N2O2
- 分子量:188.18
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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KDM4C 31 nM (Ki) |
EPZ020809 inhibits KDM4C via a 2-OG-competitive mechanism[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1503332-97-5
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分子量 188.18
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分子式 C10H8N2O2
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SMILES
O=C(C1=CC=NC(C2=CC=CN2)=C1)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Das ND, et al. Chemical Inhibitors Targeting the Histone Lysine Demethylase Families with Potential for Drug Discovery. Epigenomes. 2023;7(1):7. Published 2023 Mar 11. [Content Brief]
[2]. Wu Q, et al. Recent Advances with KDM4 Inhibitors and Potential Applications. J Med Chem. 2022;65(14):9564-9579. [Content Brief]
[3]. Wigle TJ, et al. A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening. J Biomol Screen. 2015;20(6):810-820. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
EPZ020809 関連分類
HY-183928 関連分類
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