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製品番号: HY-119512

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Ethoxomane

Name: Ethoxomane
Brand: MedChemExpress
SKU: HY-119512
Availability: PreOrder

(別名: Ethomoxane)

Ethoxomane (Ethomoxane) is an α-adrenergic receptor blocker. Ethoxomane elevates the hissing threshold induced by perifornical hypothalamic stimulation in cats. Ethoxomane exhibits antihypertensive effects. Ethoxomane can be used in the research of cardiovascular and cerebrovascular diseases.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 3570-46-5
分子式: C₁₅H₂₃NO₃
分子量:265.35

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ethoxomane 構造式

CAS 番号: 3570-46-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Adrenergic Receptor アイソフォーム固有の製品をすべて表示 :

体内実験

Ethomoxane (2.5 mg/kg; i.p.; single injection) elevates the hypothalamic-induced hissing threshold in adult mongrel cats, with a peak mean threshold increase of approximately 60%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Mongrel cats (adult; 1 male, 3 female; hypothalamic electrode implantation)^[1]
Dosage:

2.5 mg/kg (calculated as free base)
Administration:

i.p.; single injection
Result:

Elevated the hypothalamic-induced hissing threshold in all four cats, with a mean percent increase peaking at approximately 60% around 1 hour post-administration, then declining toward baseline by 2 hours post-administration.
Showed no marked changes in general animal behavior.

化学情報

CAS 番号 3570-46-5
分子量 265.35
分子式 C₁₅H₂₃NO₃
SMILES

CCOC1=C(OC(CNCCCC)CO2)C2=CC=C1
別名

Ethomoxane
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Funderburk WH, et al. Effects of psychotherapeutic drugs on hypothalamic- induced hissing in cats. Neuropharmacology. 1970 Jan;9(1):1-7. [Content Brief]

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