Fast-TRFS
Based on 2 publication(s) in Google Scholar
Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.72%
- CAS 番号: 2966536-18-3
- 分子式: C14H11F3N2O3S2
- 分子量:376.37
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
MedChemExpress(MCE)の使用を引用している文献 Fast-TRFS
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生物活性
Fast-TRFS reaches the maximal fluorescence signal within 1 min incubated with TCEP, and within 5 min incubated with the TrxR enzyme[1].
Fast-TRFS (10 μM; 2-60 min) appears the blue fluorescence signal within 2 min in HeLa cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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化学情報
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CAS 番号 2966536-18-3
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性状 Solid
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分子量 376.37
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分子式 C14H11F3N2O3S2
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Color White to light yellow
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SMILES
O=C1OC(C=C(C=C2)NC(NC3CSSC3)=O)=C2C(C(F)(F)F)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
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Journal Impact Factor
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Most Recent
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Antioxidants (Basel)
2022 Feb 13;11(2):377. PMID: 35204259 -
Microbiol Resour Announc
Redox status and metabolomic profiling of thioredoxin reductase inhibitors and 4 kGy ionizing radiation-exposed Deinococcus radiodurans. [Abstract]2022 May 13;261:127070. PMID: 35623162
溶剤 & 溶解度
DMSO : 100 mg/mL (265.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6570 mL | 13.2848 mL | 26.5696 mL | 66.4240 mL |
| 5 mM | 0.5314 mL | 2.6570 mL | 5.3139 mL | 13.2848 mL | |
| 10 mM | 0.2657 mL | 1.3285 mL | 2.6570 mL | 6.6424 mL | |
| 15 mM | 0.1771 mL | 0.8857 mL | 1.7713 mL | 4.4283 mL | |
| 20 mM | 0.1328 mL | 0.6642 mL | 1.3285 mL | 3.3212 mL | |
| 25 mM | 0.1063 mL | 0.5314 mL | 1.0628 mL | 2.6570 mL | |
| 30 mM | 0.0886 mL | 0.4428 mL | 0.8857 mL | 2.2141 mL | |
| 40 mM | 0.0664 mL | 0.3321 mL | 0.6642 mL | 1.6606 mL | |
| 50 mM | 0.0531 mL | 0.2657 mL | 0.5314 mL | 1.3285 mL | |
| 60 mM | 0.0443 mL | 0.2214 mL | 0.4428 mL | 1.1071 mL | |
| 80 mM | 0.0332 mL | 0.1661 mL | 0.3321 mL | 0.8303 mL | |
| 100 mM | 0.0266 mL | 0.1328 mL | 0.2657 mL | 0.6642 mL |