Fmoc-MMAE
Based on 1 Customer Validation
Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.35%
- CAS 番号: 474645-26-6
- 分子式: C54H77N5O9
- 分子量:940.22
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保管条件:
4°C, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
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生物活性
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Auristatin |
Fmoc-MMAE is a protective group-conjugated Monomethyl auristatin E (HY-15162).
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 474645-26-6
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性状 Solid
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分子量 940.22
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分子式 C54H77N5O9
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Color White to off-white
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SMILES
CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3C4=C(C=CC=C4)C5=C3C=CC=C5)=O)C)=O)=O)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
溶剤 & 溶解度
DMSO : ≥ 45 mg/mL (47.86 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0636 mL | 5.3179 mL | 10.6358 mL | 26.5895 mL |
| 5 mM | 0.2127 mL | 1.0636 mL | 2.1272 mL | 5.3179 mL | |
| 10 mM | 0.1064 mL | 0.5318 mL | 1.0636 mL | 2.6590 mL | |
| 15 mM | 0.0709 mL | 0.3545 mL | 0.7091 mL | 1.7726 mL | |
| 20 mM | 0.0532 mL | 0.2659 mL | 0.5318 mL | 1.3295 mL | |
| 25 mM | 0.0425 mL | 0.2127 mL | 0.4254 mL | 1.0636 mL | |
| 30 mM | 0.0355 mL | 0.1773 mL | 0.3545 mL | 0.8863 mL | |
| 40 mM | 0.0266 mL | 0.1329 mL | 0.2659 mL | 0.6647 mL |