Fomesafen-d3
Fomesafen-d3 is the deuterium-labeled Fomesafen (HY-B2010). Fomesafen is an orally active herbicide. Fomesafen inhibits protoporphyrinogen oxidase (PPO). Fomesafen induces Apoptosis and increases ROS. Fomesafen exhibits developmental toxicity, immunotoxicity, and neurotoxicity. It induces precancerous lesions in the liver and hepaturoporphyria in mice. Fomesafen is used to control broadleaf weeds in soybean fields, rubber plantations, and orchards.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C15H7D3ClF3N2O6S
- 分子量:441.78
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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非標識Cas 72178-02-0
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分子量 441.78
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分子式 C15H7D3ClF3N2O6S
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SMILES
O=C(NS(=O)(C([2H])([2H])[2H])=O)C1=CC(OC2=CC=C(C(F)(F)F)C=C2Cl)=CC=C1[N+]([O-])=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Li-Xia Zhao, et al. Novel Thiazole Phenoxypyridine Derivatives Protect Maize From Residual Pesticide Injury Caused by PPO-Inhibitor Fomesafen. Biomolecules. 2019 Sep 20;9(10):514. [Content Brief]
[2]. MACAR O, et al. FOMESAFEN-INDUCED MERISTEMATIC CELL DAMAGES IN ALLIUM CEPA L.(ONION)[J].
[3]. Xu Z, et al. Effect of fomesafen on the embryonic development of zebrafish. Chemosphere. 2020 Nov;259:127380. [Content Brief]
[4]. Krijt J, et al. Experimental hepatic uroporphyria induced by the diphenyl-ether herbicide fomesafen in male DBA/2 mice. Toxicol Appl Pharmacol. 2003 May 15;189(1):28-38. [Content Brief]
[5]. Krijt J, et al. Liver preneoplastic changes in mice treated with the herbicide fomesafen. Hum Exp Toxicol. 1999 May;18(5):338-44. [Content Brief]
[6]. Zhang Q, et al. Oxidative stress and lipid peroxidation in the earthworm Eisenia fetida induced by low doses of fomesafen. Environ Sci Pollut Res Int. 2013 Jan;20(1):201-8. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Fomesafen-d3 関連分類
HY-B2010S 関連分類
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