Crp - C-reactive protein, pentraxin-related Gene

Predicted to enable several functions, including Cholesterol binding activity; complement component C1q complex binding activity; and low-density lipoprotein particle binding activity. Predicted to be involved in several processes, including complement activation, classical pathway; regulation of gene expression; and regulation of superoxide anion generation. Predicted to act upstream of or within vasoconstriction. Predicted to be located in filopodium and growth cone. Predicted to be active in extracellular space. Is expressed in embryo and liver. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; Autoimmune Disease (multiple); macular degeneration (multiple); middle cerebral artery infarction; and Nephritis (multiple). Orthologous to human CRP (C-reactive protein). [provided by Alliance of Genome Resources, Apr 2022]