1. Immunology/Inflammation
  2. Glycoprotein VI
  3. GPVI antagonist 2

GPVI antagonist 2 (Compound 1) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 2 are, respectively, 0.35 μM for collagen, 0.80 μM for CRP, 195.2 μM for convulxin and 81.38 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 2 is a promising antiplatelet agent.

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GPVI antagonist 2 Chemical Structure

GPVI antagonist 2 Chemical Structure

CAS No. : 880399-00-8

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Description

GPVI antagonist 2 (Compound 1) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 2 are, respectively, 0.35 μM for collagen, 0.80 μM for CRP, 195.2 μM for convulxin and 81.38 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 2 is a promising antiplatelet agent[1].

Molecular Weight

421.49

Formula

C24H27N3O4

CAS No.
SMILES

O=C1N(CCCO)C(C2=CC=CC(OCCCC)=C2)C3=C1NN=C3C4=CC=CC=C4O

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GPVI antagonist 2 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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GPVI antagonist 2
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HY-115911
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