GGACK
Based on 1 Customer Validation
GGACK (H-Glu-Gly-Arg-CMK) is an irreversible substrate-like serine protease urokinase-type plasminogen activator (uPA) inhibitor.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 97.36%
- CAS 番号: 65113-67-9
- 分子式: C14H25ClN6O5
- 分子量:392.84
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U-937 | IC50 |
2.9 nM
Compound: i-uPA, Glu-Gly-Arg-chloromethyl ketone
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Inhibition of high molecular weight fluorescent labelled urokinase-type plasminogen activator binding to uPAR in PMA-stimulated human U937 cells preincubated for 30 mins by flow cytometry
Inhibition of high molecular weight fluorescent labelled urokinase-type plasminogen activator binding to uPAR in PMA-stimulated human U937 cells preincubated for 30 mins by flow cytometry
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[PMID: 21454081] |
化学情報
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CAS 番号 65113-67-9
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性状 Solid
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分子量 392.84
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分子式 C14H25ClN6O5
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Color White to off-white
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配列
Glu-Gly-Arg-{CMK}
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シーケンスの短縮
EGR-{CMK}
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : ≥ 100 mg/mL (254.56 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5456 mL | 12.7278 mL | 25.4557 mL | 63.6391 mL |
| 5 mM | 0.5091 mL | 2.5456 mL | 5.0911 mL | 12.7278 mL | |
| 10 mM | 0.2546 mL | 1.2728 mL | 2.5456 mL | 6.3639 mL | |
| 15 mM | 0.1697 mL | 0.8485 mL | 1.6970 mL | 4.2426 mL | |
| 20 mM | 0.1273 mL | 0.6364 mL | 1.2728 mL | 3.1820 mL | |
| 25 mM | 0.1018 mL | 0.5091 mL | 1.0182 mL | 2.5456 mL | |
| 30 mM | 0.0849 mL | 0.4243 mL | 0.8485 mL | 2.1213 mL | |
| 40 mM | 0.0636 mL | 0.3182 mL | 0.6364 mL | 1.5910 mL | |
| 50 mM | 0.0509 mL | 0.2546 mL | 0.5091 mL | 1.2728 mL | |
| 60 mM | 0.0424 mL | 0.2121 mL | 0.4243 mL | 1.0607 mL | |
| 80 mM | 0.0318 mL | 0.1591 mL | 0.3182 mL | 0.7955 mL | |
| 100 mM | 0.0255 mL | 0.1273 mL | 0.2546 mL | 0.6364 mL |
GGACK 関連分類
HY-137495 関連分類
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