GR 87389
GR 87389 is a potent NK2 receptor antagonist. GR 87389 antagonized GA 64349-induced smooth muscle strips contractions in a competitive manner in the human detrusor, prostate and prostatic urethra.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 141663-86-7
- 分子式: C47H65N9O9
- 分子量:900.07
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
|
NK2R |
GR 87389 is a non-peptide and peptide tachykinin antagonist with Ki values of 4.0, 5.2, and 14 nM for hippocampus, urinary bladder and duodenum, respectively[1].
GR 87389 (30-300 nM) antagonized GA 64349-induced smooth muscle strips contractions in human isolated detrusor, prostate and prostatic urethra[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 141663-86-7
-
分子量 900.07
-
分子式 C47H65N9O9
-
シーケンスの短縮
{Boc}-AA-{D-Trp}-F-{D-Pro}-P-{Nle}-NH2
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Saffroy M, et, al. Presence of NK2 binding sites in the rat brain. J Neurochem. 2001 Dec;79(5):985-96. [Content Brief]
[2]. Palea S, et, al. Pharmacological characterization of tachykinin NK2 receptors on isolated human urinary bladder, prostatic urethra and prostate. J Pharmacol Exp Ther. 1996 May;277(2):700-5. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
GR 87389 関連分類
HY-P3853 関連分類
Powered by Bioz