Heneicosane
Based on 1 publication(s) in Google Scholar
Heneicosane is a royal-specific pheromone of insects (such as subterranean termites) and is an identification signal for queens and kings in termites. Heneicosane mediates royal recognition and the maintenance of social division of labor by being sensed by worker ants and triggering vibrations and antennal behaviors. Heneicosane can exert anti-inflammatory, analgesic and antipyretic activities by inhibiting the release of inflammatory mediators (such as prostaglandins and cytokines). At the same time, Heneicosane can also inhibit the mycelial growth of aflatoxin-producing fungi and inhibit the production of aflatoxin. Heneicosane can be used in insect chemical ecology research to analyze the regulatory mechanism of termite social behavior, and is also a potential target for new anti-inflammatory drugs.
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- 純度: 99.72%
- CAS 番号: 629-94-7
- 分子式: C21H44
- 分子量:296.57
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
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MedChemExpress（MCE）の使用を引用している文献 Heneicosane
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生物活性
Heneicosane is a hydrocarbon specific to the royal family (queens and kings) of the subterranean termite Reticulitermes flavipes. Its content in the royal family is significantly higher than that in the worker termites. Heneicosane is the first confirmed pheromone for the royal family recognition of termites[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Heneicosane (1000 mg/kg; oral; once daily; for 14 consecutive days) does not cause death, behavioral abnormalities or changes in visceral morphology in the Sprague-Dawley rat acute toxicity model, confirming that it had no significant toxicity to rats at a dose of 1000 mg/kg[2].
Heneicosane (5-10 mg/kg; oral; single dose) significantly inhibits acetic acid-induced writhing reaction and formaldehyde-induced paw licking behavior (late stage) in rat models of acetic acid/formaldehyde-induced pain, carrageenan-induced inflammation, and yeast-induced fever, without significant inhibitory effect on carrageenan-induced paw edema and yeast-induced temperature increase[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 629-94-7
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性状 Solid
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分子量 296.57
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分子式 C21H44
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Color White to off-white
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SMILES
CCCCCCCCCCCCCCCCCCCCC
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
溶剤 & 溶解度
Ethanol : 10 mg/mL (33.72 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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取扱説明書 (2659 KB)
参考文献
[1]. Colin F Funaro, et al. Identification of a queen and king recognition pheromone in the subterranean termite Reticulitermes flavipes. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3888-3893. [Content Brief]
[3]. Boukaew S, et al. Efficacy of volatile compounds from Streptomyces philanthi RL-1-178 as a biofumigant for controlling growth and aflatoxin production of the two aflatoxin-producing fungi on stored soybean seeds. J Appl Microbiol. 2020 Sep;129(3):652-664. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 3.3719 mL | 16.8594 mL | 33.7189 mL | 84.2971 mL |
| 5 mM | 0.6744 mL | 3.3719 mL | 6.7438 mL | 16.8594 mL | |
| 10 mM | 0.3372 mL | 1.6859 mL | 3.3719 mL | 8.4297 mL | |
| 15 mM | 0.2248 mL | 1.1240 mL | 2.2479 mL | 5.6198 mL | |
| 20 mM | 0.1686 mL | 0.8430 mL | 1.6859 mL | 4.2149 mL | |
| 25 mM | 0.1349 mL | 0.6744 mL | 1.3488 mL | 3.3719 mL | |
| 30 mM | 0.1124 mL | 0.5620 mL | 1.1240 mL | 2.8099 mL |
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