Icterogenin
Icterogenin is a selective inhibitor targeting the Bcl-XL/Bak BH3 domain peptide interaction and exhibits anti-leukemic activity. Icterogenin regulates protein interactions and affects tumor cell survival. Icterogenin is an oleanane-type triterpenoid compound that can be isolated from Lantana camara and is useful in the field of anti-tumor drug development.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 561-47-7
- 分子式: C35H52O6
- 分子量:568.78
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Bcl-xL |
Icterogenin exhibits cytotoxicity against HL-60 human promyelocytic leukemia cells, with IC50 values ranging from 1.16 to 68.4 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 561-47-7
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分子量 568.78
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分子式 C35H52O6
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SMILES
OC([C@@]([C@@H](C1)OC(/C(C)=C\C)=O)(CC[C@]23C)[C@](CC1(C)C)([H])C2=CC[C@@]4([H])[C@]3(CC[C@]([C@](C)5CO)([H])[C@@]4(CCC5=O)C)C)=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Icterogenin 関連分類
HY-N9826 関連分類
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