IDOR-4
Based on 1 Customer Validation
IDOR-4 is a type IV CFTR corrector. IDOR-4 restores F508del-CFTR trafficking to the cell surface.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 96.98%
- CAS 番号: 2839901-24-3
- 分子式: C44H51F3N12O7
- 分子量:916.95
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
IDOR-4 (0.1-1000 nM, 24 h) restores F508del-CFTR function (YFP quenching assay), indicated by the increased F508del-CFTR C-band expression in CFBE cells, reflecting the trafficking to the cell surface[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 2839901-24-3
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性状 Solid
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分子量 916.95
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分子式 C44H51F3N12O7
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Color White to off-white
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SMILES
CC1=C2N=CC=CC2=C3C(N[C@@H](CC(N([C@H](C(N([C@@H](C(N[C@@H](COC3=C1)CC4=CC=CC=C4)=O)CC5=NC(C(F)(F)F)=NO5)C)=O)CC(C)C)C)=O)C(NCCN6N=NC(C7CC7)=N6)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : ≥ 250 mg/mL (272.64 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0906 mL | 5.4529 mL | 10.9057 mL | 27.2643 mL |
| 5 mM | 0.2181 mL | 1.0906 mL | 2.1811 mL | 5.4529 mL | |
| 10 mM | 0.1091 mL | 0.5453 mL | 1.0906 mL | 2.7264 mL | |
| 15 mM | 0.0727 mL | 0.3635 mL | 0.7270 mL | 1.8176 mL | |
| 20 mM | 0.0545 mL | 0.2726 mL | 0.5453 mL | 1.3632 mL | |
| 25 mM | 0.0436 mL | 0.2181 mL | 0.4362 mL | 1.0906 mL | |
| 30 mM | 0.0364 mL | 0.1818 mL | 0.3635 mL | 0.9088 mL | |
| 40 mM | 0.0273 mL | 0.1363 mL | 0.2726 mL | 0.6816 mL | |
| 50 mM | 0.0218 mL | 0.1091 mL | 0.2181 mL | 0.5453 mL | |
| 60 mM | 0.0182 mL | 0.0909 mL | 0.1818 mL | 0.4544 mL | |
| 80 mM | 0.0136 mL | 0.0682 mL | 0.1363 mL | 0.3408 mL | |
| 100 mM | 0.0109 mL | 0.0545 mL | 0.1091 mL | 0.2726 mL |
IDOR-4 関連分類
HY-158002 関連分類
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