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United States

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製品番号: HY-150255

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IMP2-IN-3

IMP2-IN-3 is a potent IMP2 inhibitor. IMP2-IN-3 shows anticancer effects.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 1448353-63-6
分子式: C₂₃H₂₂Cl₂N₂O₃S
分子量:477.40

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

IMP2-IN-3 構造式

CAS 番号: 1448353-63-6

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IMP2-IN-3 is a potent IMP2 inhibitor. IMP2-IN-3 shows anticancer effects^[1].

体外実験

IMP2-IN-3 (compound 9; 50 μM; 96 hours) inhibits the cell growth of Huh7 cells, it does not affect the viability of differentiated Huh7 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

Huh7 cells
Concentration:

50 μM
Incubation Time:

96 hours
Result:

Inhibited the cell growth of Huh7 cells.

化学情報

CAS 番号 1448353-63-6
分子量 477.40
分子式 C₂₃H₂₂Cl₂N₂O₃S
SMILES

O=C(C1=C(NC(N(CCC)CCC2=CC=CC=C2)=O)C=C(C3=CC(Cl)=C(Cl)C=C3)S1)O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (269 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Charlotte Dahlem, et al. First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy. ACS Chem Biol. 2022 Feb 18;17(2):361-375. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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