Isosulfazecin
Isosulfazecin (iSZ) is a novel β-lactam antibiotic produced by Pseudomonas acidophilus sp., synthesized in a nutrient solution supplemented with glycerol and sodium thiosulfate under aerobic conditions in parallel with bacterial growth. It is purified by chromatography and crystallization from aqueous methanol. Physicochemical analysis determined its molecular formula to be C12H20N4O9S, showing a structure with a β-lactam ring, methoxyl and sulfonate groups. Acid hydrolysis yields L-alanine and D-glutamic acid. iSZ is a diastereomer of sulfadiazine and exhibits moderate activity against both gram-positive and gram-negative bacteria, but potent activity against bacteria resistant to β-lactam antibiotics.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 77900-75-5
- 分子式: C12H20N4O9S
- 分子量:396.37
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Antibiotic アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
化学情報
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CAS 番号 77900-75-5
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分子量 396.37
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分子式 C12H20N4O9S
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SMILES
OC([C@H](N)CCC(N[C@@H](C)C(N[C@@]1(C(N(S(=O)(O)=O)C1)=O)OC)=O)=O)=O
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Structure Classification
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Initial Source
Pseudomonas mesoacidophila sp.
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Isosulfazecin 関連分類
HY-121120 関連分類
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