Izuralimab
Based on 1 Customer Validation
Izuralimab is a bispecific IgG1 antibody targeting inducible T-cell costimulator (ICOS/CD278) and PD-1.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.97%
- CAS 番号: 2329669-80-7
- 分子量:126.283 kDa
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
half-IGG1-kappa/(scFv-kappa-heavy)-h-CH2-CH3
Human
PDCD1 & ICOS
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
-
half-IGG1-kappa/(scFv-kappa-heavy)-h-CH2-CH3
ELISA, FACS, Functional assay
-
Immobilized PD-1 Protein, Human (143a.a, HEK293, His, HY-P7396) can bind Izuralimab. The EC50 for this effect is 8.806 ng/mL. -
Immobilized ICOS Protein, Human (HEK293, Fc, HY-P72618) can bind Izuralimab. The EC50 for this effect is 62.25 ng/mL.
化学情報
-
CAS 番号 2329669-80-7
-
性状 Liquid
-
分子量 126.283 kDa
-
Color Colorless to light yellow
-
SMILES
[Izuralimab]
-
輸送条件
Shipping with dry ice.
-
Formulation
Please refer to the lot-specific COA for specific buffer information.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
-
データシート (255 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Inhibitory Antibodies User Guide (603 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)