KY0418
KY0418 is a selective GPX4 inhibitor. KY0418 selectively and covalently modifies the selenocysteine residue of GPX4 and inhibits GPX4 activity. KY0418 induces ferroptosis and suppresses cell proliferation. KY0418 can be used for the study of ferroptosis and cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3024369-07-8
- 分子式: C28H35F3N8O3
- 分子量:588.62
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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GPX4 |
KY0418 (E46) potently inhibits proliferation of 786-O cells with an IC50 ≤ 100 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3024369-07-8
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分子量 588.62
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分子式 C28H35F3N8O3
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SMILES
O=C(N1C2=CC=C(N3C[C@H](C)O[C@H](C)C3)N=C2)C4(CCCC4)C5=C1N=C(COC(N6[C@@H](C(F)(F)F)CCC6)=N)N=C5N
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
KY0418 関連分類
HY-186143 関連分類
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