LabMol-301
LabMol-301 inhibits both NS5 RdRp and NS2B-NS3pro activity (IC50: 0.8 and 7.4 μM, respectively). LabMol-301 has a cytoprotective effect and prevents Zika virus (ZIKV)-induced cell death.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1360243-08-8
- 分子式: C18H16N6
- 分子量:316.36
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
NS5 RdRp, NS2B-NS3pro[1]
LabMol-301 (20 μM) shows 99% inhibition rate of NS5 RdRp activity[1].
LabMol-301 (10 μM) inhibits more than 80% of the NS2B-NS3pro protease activity[1].
LabMol-301 interacts with ZIKV NS2B-NS3pro at the allosteric site relied on a highly hydrophobic complementarity between the molecule’s surfaces and the protein[1].
LabMol-301 is able to protect GSC387 cell from cell death induced by ZIKV (EC50: 6.68 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1360243-08-8
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分子量 316.36
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分子式 C18H16N6
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SMILES
NC1=C(C2=C3C(NC=C3)=NC(NCC4=CC=CN=C4)=C2)C=NC=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
LabMol-301 関連分類
HY-151526 関連分類
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