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製品番号: HY-114780

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Lactivicin

Lactivicin is a non-beta-lactam antibiotic showing beta-lactam action through binding to penicillin-binding protein (PBP). Lactivicin is moderately active against a wide range of Gram-negative bacteria and highly active against Gram-positive bacteria.

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CAS 番号: 107167-31-7
分子式: C₁₀H₁₂N₂O₇
分子量:272.21

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Lactivicin 構造式

CAS 番号: 107167-31-7

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Bacterial InfectionOthers

Bacterial Infection

Lactivicin exhibits moderate activity against most Gram-negative bacteria, high activity against Gram-positive and anaerobic bacteria, and significantly enhanced activity against β-lactam hypersensitive mutants E. coli PG-8 (MIC = 0.78 μg/mL) and P. aeruginosa C 141 (MIC = 0.2 μg/mL)^[2].
Lactivicin (100-1000 μg/mL) is highly susceptible to cephalosporinases and hydrolysed by multiple penicillinases, with full stability only against Bacillus cereus penicillinase^[2].
Lactivicin (0.5-10× MIC) lyses E. coli LD-2 cells and induces spheroplasts at 1× MIC, while causing growth stasis at concentrations above 5× MIC^[2].
Lactivicin (0.5-10× MIC) exhibits dose-dependent lytic activity against B. subtilis PCI 219, inducing filamentous cells at 1× MIC and strong lysis at concentrations above 5× MIC^[2].

Others

Lactivicin (0.5-20 μg/mL; 2 h) potently inhibits peptidoglycan synthesis in B. subtilis PCI 219 in a dose-dependent manner^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Gram Staining of Tissue Sections

化学情報

CAS 番号 107167-31-7
分子量 272.21
分子式 C₁₀H₁₂N₂O₇
SMILES

O=C(O)C(N1OC[C@@H](C1=O)NC(C)=O)(O2)CCC2=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (268 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Nozaki Y, et al. Lactivicin, a naturally occurring non-beta-lactam antibiotic having beta-lactam-like action: biological activities and mode of action. J Antibiot (Tokyo). 1989 Jan;42(1):84-93. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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