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United States

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製品番号: HY-119325

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Lanperisone

(別名: NK433 free base)

Lanperisone is a novel oral muscle relaxant with anticancer activity. Lanperisone produces non-apoptotic cell death by inhibiting monosynaptic and polysynaptic reflex potentials. Lanperisone is also believed to play an important role in the dysregulation of iron metabolism and antioxidant systems to modulate processes associated with ischemic stroke.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 116287-14-0
分子式: C₁₅H₁₈F₃NO
分子量:285.30

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Lanperisone 構造式

CAS 番号: 116287-14-0

容量

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数量

Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
MEF	IC₅₀	4 μM Compound: 7	Cytotoxicity against MEF harboring KRAS G12D mutant by ATP-based cell viability assay Cytotoxicity against MEF harboring KRAS G12D mutant by ATP-based cell viability assay	[PMID: 23566315]
MEF	IC₅₀	4 μM Compound: 7	Antiproliferative activity against mouse MEF cells expressing KRAS G12D mutant assessed as reduction in cell viability incubated for 48 hrs by CellTiter-Glo luminescent assay Antiproliferative activity against mouse MEF cells expressing KRAS G12D mutant assessed as reduction in cell viability incubated for 48 hrs by CellTiter-Glo luminescent assay	[PMID: 36332549]
MEF	IC₅₀	4 μM Compound: Lanperisone	Cytotoxicity against MEF expressing K-rasG12D after 48 hrs by CellTiter-Glo assay Cytotoxicity against MEF expressing K-rasG12D after 48 hrs by CellTiter-Glo assay	[PMID: 22297109]

化学情報

CAS 番号 116287-14-0
分子量 285.30
分子式 C₁₅H₁₈F₃NO
SMILES

O=C([C@@H](CN1CCCC1)C)C2=CC=C(C=C2)C(F)(F)F
別名

NK433 free base
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (264 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Tian X, et al. Progress of Ferroptosis in Ischemic Stroke and Therapeutic Targets. Cell Mol Neurobiol. 2024 Feb 23;44(1):25. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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分子量分子量

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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