脂質ナノ粒子 LNP 封入サービス
MCE offers one-stop lipid nanoparticle (LNP) formulation services, professionally supporting the delivery of mRNAs, circular RNAs (circRNAs), self-amplifying RNAs (saRNAs), siRNAs, sgRNAs, and DNAs. Leveraging optimized lipid formulations and precision-targeted ligands, MCE ensures efficient, stable delivery of payloads to target tissues and cells, providing reliable technical support and solutions for your R&D projects.
Furthermore, MCE provides the full workflow covering gene synthesis, plasmid preparation, linearization, IVT RNA production, and LNP encapsulation, significantly shortening development timelines and reducing project costs, helping you accelerate the project progress.
For small-molecule compounds, MCE also provides customized LNP formulation services, with tailored solutions developed based on a professional assessment of each compound's structure and physicochemical properties. Representative applications include doxorubicin hydrochloride liposomes and paclitaxel liposomes, addressing diverse drug delivery needs.
Optional Formulations
- Ionizable lipid formulations: MC3-LNP / SM102-LNP / ALC0315-LNP
- Organ targeted LNPs: lung, spleen, liver, kidney and heart, etc
- other customized LNPs
QC Testing
- Appearance
- Concentration
- Encapsulation efficiency
- Size distribution (POI)
- polydispersity index (PDI)
- Zeta potential
- pH
- Endotoxin
Optional Payloads
- 20 nt-20 kb mRNA, siRNA, miRNA, circRNA, saRNA and DNA, etc
- Small molecule compounds
Shipping/Storage
- Liquid delivery (some of the products available in the form of freeze-dried powder)
- Shipping with dry ice
- Avoid freeze–thaw cycles
Popular Liposomes & LNPs catalogs available now!
Try our ready-to-use liposomes & LNPs pre-loaded with mRNA, or active compounds.
| Cat. No. | Product Name |
|---|---|
| HY-153229 | Firefly luciferase mRNA-LNP |
| HY-153232 | eGFP circRNA-LNP |
| HY-153235 | COVID-19 Spike Protein mRNA-LNP |
| HY-153230 | Firefly luciferase circRNA-LNP |
| HY-153231A | eGFP mRNA-LNP (500 ng/μL) |
| HY-172202 | Clodronate liposomes |
| Cat. No. | Product Name |
|---|---|
| HY-185370 | Doxorubicin liposome |
| HY-185373 | Paclitaxel liposome |
| HY-177846 | Liposomal Melatonin |
| HY-177843 | Liposomal NMN |
| HY-177829 | Liposomal Vitamin C |
| HY-177839 | Liposomal Coenzyme Q10 |
Service and Consulting
The corresponding scheme and price for LNP formulation services shall be determined after evaluation. For further information on service prices or technical details, please send an email to sales [email protected] or contact MedChemExpress sales staff directly.