LSD1-IN-40
LSD1-IN-40 (Compound 9e) is a potent LSD1 inhibitor, with an IC50 of 9.85 nM. LSD1-IN-40 exhibits exceptional selectivity for LSD1 over both MAOs and hERG. LSD1-IN-40 exhibits significant inhibitory activity against leukemia cells (MV-4-11, HL-60, and THP-1 cells). LSD1-IN-40 can induce apoptosis in MV-4-11 cells. LSD1-IN-40 has the potential for the research of acute myeloid leukemia.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C25H20F2N6O2S
- 分子量:506.53
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
化学情報
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分子量 506.53
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分子式 C25H20F2N6O2S
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SMILES
O=S(C1=CC=CC=C1)(N2C(C=CC(N3C=C(CN[C@@H]4C[C@H]4C5=CC=C(F)C(F)=C5)N=N3)=C6)=C6C=N2)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)