m-PEG4-SH
Based on 1 Customer Validation
m-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.84%
- CAS 番号: 52190-55-3
- 分子式: C9H20O4S
- 分子量:224.32
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保管条件:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 52190-55-3
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性状 Liquid (Density: 1.035 g/cm3)
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分子量 224.32
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分子式 C9H20O4S
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Color Colorless to light yellow
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SMILES
COCCOCCOCCOCCS
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (445.79 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (761 KB)
- English - EN (761 KB)
- Français - FR (761 KB)
- Deutsch - DE (761 KB)
- Norwegian - NO (761 KB)
- Español - ES (761 KB)
- Swedish - SV (761 KB)
- Italian - IT (761 KB)
- Korean - KR (761 KB)
- Portuguese - PT (761 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4579 mL | 22.2896 mL | 44.5792 mL | 111.4479 mL |
| 5 mM | 0.8916 mL | 4.4579 mL | 8.9158 mL | 22.2896 mL | |
| 10 mM | 0.4458 mL | 2.2290 mL | 4.4579 mL | 11.1448 mL | |
| 15 mM | 0.2972 mL | 1.4860 mL | 2.9719 mL | 7.4299 mL | |
| 20 mM | 0.2229 mL | 1.1145 mL | 2.2290 mL | 5.5724 mL | |
| 25 mM | 0.1783 mL | 0.8916 mL | 1.7832 mL | 4.4579 mL | |
| 30 mM | 0.1486 mL | 0.7430 mL | 1.4860 mL | 3.7149 mL | |
| 40 mM | 0.1114 mL | 0.5572 mL | 1.1145 mL | 2.7862 mL | |
| 50 mM | 0.0892 mL | 0.4458 mL | 0.8916 mL | 2.2290 mL | |
| 60 mM | 0.0743 mL | 0.3715 mL | 0.7430 mL | 1.8575 mL | |
| 80 mM | 0.0557 mL | 0.2786 mL | 0.5572 mL | 1.3931 mL | |
| 100 mM | 0.0446 mL | 0.2229 mL | 0.4458 mL | 1.1145 mL |